Background highoutput heart failure hf is an unusual cause of cardiac failure that has not been wellcharacterized. With highoutput heart failure, the heart is pumping a normal amount of blood, but its still not enough to help the body work the way it should. Clinical presentation patients can present with a number of symp. An elevated cardiac output with clinical heart failure is associated with several diseases including chronic anaemia, systemic arteriovenous fistulae, sepsis, hypercapnia and hyperthyroidism. School of biomedical science, charles sturt university, specialist in anaesthesia and intensive care, bathurst base hospital, bathurst, nsw, australia. High output failure ci inc, lvedv inc, lvedp n systolic failure.
Most of the high output patients presented with leftsided hf n 91, 76%, and the remaining presented with right heart failure. This continuing education course for healthcare professionals explores the causes, clinical presentation, diagnosis and management of heart failure. The heart and cardiac output managing cardiac emergencies relies heavily on an ability to recognize, understand and respond to altered cardiac output. Betablockers are well known to depress lv systolic function i. Varga on what are the causes of high cardiac output. The heart and cardiac output 911 tactical medicine. Pdf on sep 5, 2015, mingzheng aaron goh and others published high output cardiac failure following formation of an axilloiliac arteriovenous graft for haemodialysis find, read and cite all. Ive tried looking at multiple resources but i cant wrap my head around this. Vein of galen malformation and highoutput cardiac failure. Heart failure is a chronic condition affecting millions of people today. There are several cardiac manifestations of thyrotoxicosis, including enlargement of the heart, atrial fibrillation, high output heart failure, hypertrophic cardiomyopathy, anginal syndrome without evidence of coronary artery disease, and sudden death. Evidence and guidelines for the treatment of highoutput heart failure are scarce. These individuals usually have a normal systolic function but symptoms are those of heart failure.
These conditions cause ventricular dysfunction with low cardiac output, which. The hemodynamic changes associated with liver transplantation for highoutput heart failure are described. Cardiac output is usually normal or low in patients with heart failure hf, but a minority of patients present in a high output state, which has historically been referred to as high output hf 1, 2. Patients with highoutput heart failure demon strate higher ejection fraction and eccentric remodeling of the ventricle, including greater ventricular mass and size. Various physiologic, pathologic and iatrogenic aetiologies can lead to this. Redfield, margaret m nishimura, rick a borlaug, barry a. In rare cases, high output chf may occur as a result of conditions that increase cardiac output and thereby overwhelm the heart. Congestive heart failure describes a syndrome with complex and variable symptoms and signs, including dyspnea, increased fatigability, tachypnea, tachycard. Evidence and guidelines for the treatment of high output heart failure are scarce. Congestive heart failure free online course materials. While most patients with heart failure hf, with either reduced or preserved ejection fraction, have low or normal cardiac output accompanied by elevated systemic vascular resistance, a minority of patients with hf present with a highoutput state with low systemic vascular resistance.
Highoutput heart failure is a heart condition that occurs when the cardiac output is higher than normal due to increased peripheral demand. Congestive heart failure knowledge for medical students. Or failure caused by maintaining a high cardiac output for too long. These individuals usually have a normal systolic function but symptoms. High output cardiac failure associate professor brendan e. The syndrome of systemic congestion in a high output state is traditionally referred to as high output heart failure. The syndrome of heart failure hf is characterized by exercise intolerance, limited by dyspnea and fatigue, and associated with neurohormonal activation and fluid retention. Hemodynamic changes in highoutput cardiac failure by. Because cardiac output is related to the quantity of blood delivered to. High output heart failure high output heart failure mehta, p. Cardiac output, high definition of cardiac output, high by. Decompensated heart failure paradigms epidemiology heart failure.
A 40yearold woman was scheduled for olt due to a major intrahepatic avf, responsible for highoutput cardiac failure. Usually, if you have heart failure, your heart isnt pumping enough blood through your body to help it work the way it should. The most obvious causative factors are pathologic changes in the hearts muscle or electrical conduction system, congenital. Anemia systemic arteriovenous fistulas hyperthyroidism beriberi heart disease paget disease of bone glomerulonephritis polycythemia vera carcinoid syndrome obesity heart failure. What are the causes of high cardiac output answers on. The three main causes of chf are coronary heart disease, diabetes mellitus, and hypertension. Usually, if you have heart failure, your heart isnt pumping enough blood through your body to help it. Congestive heart failure simply means that the pulmonary blood volume is expanded and, therefore, the pulmonary circulation is congested with blood. High output heart failure in a young woman secondary to. A female singleton is delivered at 30 67 weeks gestational age via cesarean for preterm labor and breech presentation.
There is a circulatory overload which may lead to pulmonary edema secondary to an elevated diastolic pressure in the left ventricle. Echocardiography revealed high cardiac output 10 lmin with preserved left ventricular ejection fraction 65% and pulmonary hypertension 45 mm hg. High output heart failurea reversible cause missed again. High output cardiac failure refers to a state of cardiac failure that is associated with a higher than normal cardiac output which is still not sufficient for body tissue demands. Inducible and reversible intrapulmonary arteriovenous shunt. However, betablockers have been found to offer an important mortality benefit to patients with congestive heart failure. High output cardiac failure is a rare complication of hereditary hemorrhagic telangiectasia and can potentially be mistaken for other entities. Aug 02, 2016 high output heart failure high output heart failure reddy, yogesh n. Highoutput cardiac failure statpearls ncbi bookshelf. We report the case of a child, currently 12months old. Control subjects free of hf enrolled in a separate prospective study. The term congestive heart failure is often used, as one of the common symptoms is congestion, or buildup of fluid in a persons tissues and veins in the lungs or other parts of the body.
Highoutput heart failure, journal of the american college. Heart failure is a pathophysiological state in which cardiac output is insufficient to meet the needs of the body and lungs. Congestive heart failure knowledge for medical students and. Echocardiography revealed high cardiac output 10 lmin with preserved left.
Can someone explain what high output cardiac failure is. For patients who are drinking excessive alcohol and. In the absence of heart failure, an increase in arterial resistance does not reduce cardiac output. Chf is diagnosed based on clinical presentation and requires an initial.
What are the causes of high cardiac output answers on healthtap. Cardiac output is usually normal or low in patients with heart failure hf, but a minority of patients present in a highoutput state, which has historically been referred to as highoutput hf 1, 2. Objectives this study sought to characterize the etiologies, pathophysiology, clinical and hemodynamic characteristics, and outcomes of highoutput hf in the modern era. Methods we performed a retrospective analysis of all consecutive patients referred to the mayo clinic.
Highoutput heart failure article about highoutput heart. Pdf high output cardiac failure following formation of. Congestive heart failure describes a syndrome with complex and variable symptoms and signs, including dyspnea, increased fatigability, tachypnea, tachycardia, pulmonary rales, and peripheral edema. Find out information about high output heart failure. Physiological causes include pregnancy, fever and illness. Co values can be represented using many physical units, such as dm 3 min and lmin. Although this syndrome usually is associated with low cardiac output, it may occur in a number of socalled high output states, when the cardiac output is. Highoutput heart failure hf is an unusual cause of cardiac failure that. Pdf on sep 5, 2015, mingzheng aaron goh and others published high output cardiac failure following formation of an axilloiliac arteriovenous graft for haemodialysis.
Definition of high output cardiac state and heart failure. Many of the treatments utilized for other forms of heart failure, such as vasodilatators, may worsen hemodynamic. The neurohormonal response observed in these highoutput conditions is almost identical to that. Highoutput heart failure in sickle cell anemia jacc. High output heart failure article about high output heart. The association of thyrotoxicosis and cardiovascular morbidity is well established. Early diagnosis and treatment can help people who have heart failure live longer, more active lives. The increased venous return can lead to an elevated doppler ee. The pregnancy is notable for severe fetal anemia, highoutput cardiac failure with normal cardiac anatomy, polyhydramnios, and a placental chorioangioma diagnosed at 26 weeks of gestation.
The mother is a 37yearold grand multipara in her 10th pregnancy. An overall concept of cardiovascular physiology should accommodate these. Assuming a true high cardiac output syndrome, patients may feel flushed with a fast heart rate. Causes of highoutput cardiac failure can be simplified into two main. Although this syndrome usually is associated with low cardiac output, it may occur in a number of socalled high output states, when the cardiac output is normal or greater than normal. This is because systemic disorders and diseases affect both organs alcohol abuse, drugs, inflammation, autoimmunity, infections and because of complex cardiohepatic interactions.
Video must be watched to completion to be eligible for full credit. The study cohort was comprised of 525 hf patients that showed an elevated cardiac index, of whom 120 cases had definite high output hf. Lastly, with severely reduced ejection fractions and cardiac conduction defects, cardiac. Read more about symptoms, diagnosis, treatment, complications, causes and prognosis.
Highoutput heart failure highoutput heart failure reddy, yogesh n. Highoutput heart failure in a newborn bmj case reports. Clinic observation on d1 was normal except for the presence of a systolic cardiac murmur. By understanding the factors that influence cardiac output, memory work becomes unnecessary. In all highoutput hf states where the co is increased, such as in chronic severe anemia, chronic obstructive pulmonary disease, and large arteriovenous fistula, the arterial blood pressure is also threatened or is reduced because of severe vasodilatation. Highoutput cardiac failure is a less common form of heart failure, and although it may. Highoutput heart failure, journal of the american college of. The primary stimulus that signals the kidney to retain salt and water is debated. Congestive heart failure chf is a clinical condition in which the heart is unable to pump enough blood to meet the metabolic needs of the body because of pathological changes in the myocardium. High output cardiac failure is an uncommon cause of heart failure. High output heart failure request pdf researchgate. Objectives this study sought to characterize the etiologies, pathophysiology, clinical and hemodynamic characteristics, and outcomes of high output hf in the modern era. While most patients with heart failure hf, with either reduced or preserved ejection fraction, have low or normal cardiac output accompanied by elevated systemic vascular resistance, a minority of patients with hf present with a high output state with low systemic vascular resistance. This chapter serves as a beginning in the process of.
With the highoutput version, its pumping a normal amount of blood or even more than normal. These findings led the physicians to suspect septic shock of pulmonary origin. High output heart failure is a heart condition that occurs when the cardiac output is higher than normal due to increased peripheral demand. The pregnancy is notable for severe fetal anemia, highoutput cardiac failure with normal cardiac anatomy, polyhydramnios, and a placental chorioangioma diagnosed at 26.
Highoutput cardiac failure radiology reference article. Its also very different from other types of the disorder. High output heart failure article about high output. An elevated cardiac output with clinical heart failure is associated with several diseases including chronic anaemia, systemic. Highoutput heart failure american college of cardiology. Cardiac output, high definition of cardiac output, high. Pdf high output cardiac failure following formation of an. Highoutput heart failure happens when the bodys need for blood is unusually high, so heart failure symptoms happen even though the heart is working well. Background high output heart failure hf is an unusual cause of cardiac failure that has not been wellcharacterized.
A high cardiac output has been described as being 8 lmin or a cardiac index 3. Nov 01, 2018 a female singleton is delivered at 30 67 weeks gestational age via cesarean for preterm labor and breech presentation. The symptoms and signs of heart failure can occur in the setting of an increased cardiac output and has been termed high output heart failure. Highoutput heart failure may occur if systemic vasodilation decreases relative renal perfusion to the point of causing salt and water retention, elevated filling pressures, and the syndrome of clinical heart failure. Heart failure may occur if the heart is overstrained as a result of arterial hypertension or heart disease or if the blood supply to the heart is interrupted myocardial infarction. Three major mechanisms for highoutput heart fail ure include large extracardiac lefttoright shunt, body metabolism overstimulation. With loss of the placenta at birth, up to 70% of cardiac output is directed to vgams lowresistance arteriovenous shunt that allows direct return of large flow volume to the right heart.
The study cohort was comprised of 525 hf patients that showed an elevated cardiac index, of whom 120 cases had definite highoutput hf. After intubation, the patient underwent fluid resuscitation and received continuous intravenous epinephrin infusion. Most are transient situations, but some illnesses and conditions may cause a sustained high output state, e. Classical heart failure treatment can be detrimental in this instance. Specifically, congestion takes the form of water retention and. Highoutput cardiac failure due to hereditary hemorrhagic. Premature infant with anemia and highoutput cardiac. Highoutput heart failure definition of highoutput heart. High output heart failure is a poorly understood condition characterized by signs and symptoms of heart failure and a resting cardiac index above 4 lmin x m2. Acute decompensated heart failure may occur as an exacerbation of chf or be caused by an acute cardiac condition such as myocardial infarction. When measuring output for a patient record, the volume of urine, drainage from tubes, vomitus, and any other measurable liquid should be recorded. Most of the highoutput patients presented with leftsided hf n 91, 76%, and the remaining presented with right heart failure. A high output state may occur in chronic severe anemia, large arteriovenous fistula or multiple small arteriovenous shunts as in pagets bone disease, some forms of severe hepatic or renal disorders, and acutely in septic shock.
497 96 1254 688 592 280 282 679 516 1396 382 451 1376 1432 1111 1313 311 1421 481 1070 1180 929 824 247 1237 1368 65 1354 200 414 1058 177 1114 717 890 247 1435